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Home > RNA Biology > Publications
Home > RNA Biology > Publications
Research unit director
Couvertures de revues
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Publications

PUBLICATIONS RÉCENTES

(Les noms en caractère Gras indiquent les membres du labo)

Lefebvre FA, Cody NAL, Bouvrette LPB, Bergalet J, Wang X. and Lécuyer E. CeFra-seq: Systematic mapping of RNA subcellular distribution properties thought cell fractionation coupled to deep-sequencing. Methods. (2017) 126:138-148.

Chin A. and Lécuyer E. RNA Localization: Making its way to the centerstage. Biochemica et Biophysica Acta. (2017) 1861(11):2956-2970.

Lefebvre FA, Benoit Bouvrette LP, Bergalet J. and Lécuyer E. Biochemical Fractionation of Time-Resolved Drosophila Embryos Reveals Similar Transcriptomic Alterations in Replication Checkpoint and Histone mRNA Processing Mutants. (2017) J. Mol. Biol.; 429(21):3264-3279.

Eric L Van Nostrand, Peter Freese, Gabriel A Pratt, Xiaofeng Wang, Xintao Wei, Steven M Blue, Daniel Dominguez, Neal A L Cody, Sara Olson, Balaji Sundararaman, Rui Xiao, Lijun Zhan, Cassandra Bazile, Louis Philip Benoit Bouvrette, Jiayu Chen, Michael O Duff, Keri Garcia, Chelsea Gelboin-Burkhart, Abigail Hochman, Nicole J Lambert, Hairi Li, Thai B Nguyen, Tsultrim Palden, Ines Rabano, Shashank Sathe, Rebecca Stanton, Ashley L Louie, Stefan Aigner, Julie Bergalet, Bing Zhou, Amanda Su, Ruth Wang, Brian A Yee, Xiang-Dong Fu, Eric Lecuyer, Christopher B Burge, Brenton Graveley, Gene W Yeo. A Large-Scale Binding and Functional Map of Human RNA Binding Proteins. Nature. Submitted

Diot C, Chin A and Lécuyer E. Optimized FISH methods for visualizing RNA localization properties in Drosophila and human tissues and cultured cells. Methods. (2017); 126:156-165.

Benoit Bouvrette LP, Cody NAL, Bergalet J, Lefebvre FA, Diot C, Wang X, Blanchette M. and Lécuyer E. CeFra-seq reveals broad asymmetric mRNA and non-coding RNA distribution profiles in Drosophila and human cells. (2017) [Epub ahead of print)

ENCODE Phase III: Building an encyclopedia of candidate regulatory elements for human and mouse. Nature. Submitted

Fabio A. Lefebvre and Eric Lécuyer. Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication. (2017), Front Microbiol.; Volume 8, Article 377

Fabio Alexis Lefebvre, Louis Philip Benoit Bouvrette, Julie Bergalet and Eric Lécuyer. Data for the generation of RNA spatiotemporal distributions and interpretation of Chk1 and SLBP protein depletion phenotypes during Drosophila embryogenesis. Data Brief (2017) 13: 28–31.

Kowanda, M. Bergalet, J., Wieczorek, M., Brouhard, G., Lécuyer, E., and Lasko, P.(2016). Loss of function of the Drosophila Ninein-relatedcentrosomal protein Bsg25D causes mitotic defects and impairs embryonic development. Biology Open. 5(8): 1040-1051.

Lefebvre FA, Bouvrette LP, Perras L, Blanchet-Cohen A, Garnier D, Rak J, Lécuyer E. (2016). Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation. Scientific Reports. 6:27680.

Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, Wei X, Van Nostrand EL, Huelga SC, Smalec BM, Wang X, Hong EL, Davidson JM, Lecuyer E, Graveley BR, Yeo GW. (2016). Resources for the comprehensive discovery of functional RNA elements. Molecular Cell. 61(6):903-13.

Gerby B., Tremblay C.S., Tremblay M., Rojas-Sutterlin S., Hébert J., Sauvageau G., Lemieux S., Lécuyer E., Veiga D.F.T. and Hoang T. (2014). SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells.PLoS Genetics. 10: e1004768.

Iampietro, C., Bergalet, J., Wang, X., Cody, N.A., Chin, A., Lefebvre, F.A., Douziech, M., Krause, H.M., and Lécuyer, E. 2014. Developmentally-regulated elimination of damaged nuclei via a Chk2-dependent mechanism of mRNA nuclear retention. Developmental Cell, 29(4):468-81

Rojas-Sutterlin, S., Lécuyer, E., Hoang, T. 2014. Kit and Scl regulation of hematopoietic stem cells. Current Opinion in Hematology, 21(4), p 256–264.

Bergalet, J. and Lécuyer, E. 2014. The functions and regulatory principles of mRNA intracellular trafficking. In book on 'Systems and molecular perspectives to RNA binding protein biology' Edited by Gene Yeo. Adv Exp Med Biol, 825:57-96.

Bergalet, J., Iampietro, C., Chin, A., Oré-Rodriguez, S., Nguyen, X.-T., Cody, N.A., and Lécuyer, E. 2014. High-resolutions FISH procedures in Drosophila. In book on 'In situ hybridization methods' edited by Giselbert Hauptmann. Neuromethods. 714:31-47.

Cody, N.A., Iampietro, C., and Lécuyer, E. 2013. The many functions of mRNA localization during normal development and disease: from pillar to post. WIREs Dev Biol 2:781-96.

Zhang, Y,, Ponty, Y., Blanchette, M., Lécuyer, E., and Waldispühl, J. 2013. SPARCS: a web server to analyze (un)structured regions in coding RNA sequences. Nucleic Acids Res 41(Web Server issue):W480-5.

Legendre F, Cody N, Iampietro C, Bergalet J, Lefebvre FA, Moquin-Beaudry G, Zhang O, Wang X, and Lécuyer E. 2013. Whole mount RNA fluorescent in situ hybridization of Drosophila embryos. J Vis Exp 71, e50057.

Wang, E.T., Cody, N.A., Jog, S., Biancollela, M., Wang, T.T., Treacy, D.J., Luo, S., Schroth, G.P., Housman, D.E., Reddy, S., Lécuyer, E., and Burge, C.B. 2012. Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins. Cell  150:710-24.

Lécuyer, E. 2011. High resolution fluorescent in situ hybridization in Drosophila. Methods in Molecular Biology 714: 31-47. Edited by J. E. Gerst, Humana Press Inc.

Lécuyer, E., Yoshida, H., and Krause, H.M. 2009. Global implications of mRNA localisation pathways in cellular organisation. Curr Opin Cell Biol 3, 409-15.

Lécuyer, E., Nećakov, A.S., Cáceres, L. and Krause, H.M. 2008. High-resolution fluorescent in situ hybridization of Drosophila embryos and tissues. CSH Protocols, doi:10.1101/pdb.prot5019.

Lécuyer, E., Parthasarathy, N., and Krause, H.M. 2008. Fluorescent in situ hybridization protocols in Drosophila embryos and tissues. Methods in Molecular Biology 420: 289-302. Edited by C. Dahmann, Humana Press Inc.

Lécuyer, E., and Tomancak, P. 2008. Mapping the gene expression universe. Curr Opin Genet Dev 6, 506-12.

Lécuyer, E. 2008. Le code de localisation des ARNm se révèle. Med. Sci. (Paris) 24, 350-1.

Lécuyer, E., Yoshida, H., Parthasarathy, N., Alm, C., Babak, T., Cerovina, T., Hughes, T.R., Tomancak, P., and Krause, H. M. 2007. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell 131, 174-87.


AUTRES PUBLICATIONS

Lécuyer, E., Larivière, S., Sincennes, M.-C., Haman, A., Lahlil, R., Todorova, M., Tremblay, M., Wilkes, B.C., and Hoang, T. 2007. Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction. J. Biol. Chem. 282, 33649-58.

Lahlil, R.*, Lécuyer, E.*, Herblot, S., and Hoang, T. 2004. SCL assembles a multifactorial complex that determines glycophorin A gene expression. Mol. Cell. Biol. 24, 1439-52.
*= Contributions égales par ces auteurs.

Lécuyer, E., and Hoang, T. 2004. SCL: from the origin of hematopoiesis to stem cells and leukemia. Exp. Hematol. 32, 11-24.

Tremblay, M., Herblot, S., Lécuyer, E., and Hoang, T. 2003. Regulation of pT alpha gene expression by a dosage of E2A, HEB and SCL. J. Biol. Chem. 278, 12680-7.

Lécuyer, E., Herblot, S., St-Denis, M., Martin, R., Begley, C.G., Porcher, C., Orkin, S.H., and Hoang, T. 2002. The SCL-complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1. Blood 100, 2430-40.

RECENT PUBLICATIONS

(Names in Bold indicate members of the Lécuyer lab)

Lefebvre FA, Cody NAL, Bouvrette LPB, Bergalet J, Wang X. and Lécuyer E. CeFra-seq: Systematic mapping of RNA subcellular distribution properties thought cell fractionation coupled to deep-sequencing. Methods. (2017) 126:138-148.

Chin A. and Lécuyer E. RNA Localization: Making its way to the centerstage. Biochemica et Biophysica Acta. (2017) 1861(11):2956-2970.

Lefebvre FA, Benoit Bouvrette LP, Bergalet J. and Lécuyer E. Biochemical Fractionation of Time-Resolved Drosophila Embryos Reveals Similar Transcriptomic Alterations in Replication Checkpoint and Histone mRNA Processing Mutants. (2017) J. Mol. Biol.; 429(21):3264-3279.

Eric L Van Nostrand, Peter Freese, Gabriel A Pratt, Xiaofeng Wang, Xintao Wei, Steven M Blue, Daniel Dominguez, Neal A L Cody, Sara Olson, Balaji Sundararaman, Rui Xiao, Lijun Zhan, Cassandra Bazile, Louis Philip Benoit Bouvrette, Jiayu Chen, Michael O Duff, Keri Garcia, Chelsea Gelboin-Burkhart, Abigail Hochman, Nicole J Lambert, Hairi Li, Thai B Nguyen, Tsultrim Palden, Ines Rabano, Shashank Sathe, Rebecca Stanton, Ashley L Louie, Stefan Aigner, Julie Bergalet, Bing Zhou, Amanda Su, Ruth Wang, Brian A Yee, Xiang-Dong Fu, Eric Lecuyer, Christopher B Burge, Brenton Graveley, Gene W Yeo. A Large-Scale Binding and Functional Map of Human RNA Binding Proteins. Nature. Submitted

Diot C, Chin A and Lécuyer E. Optimized FISH methods for visualizing RNA localization properties in Drosophila and human tissues and cultured cells. Methods. (2017); 126:156-165.

Benoit Bouvrette LP, Cody NAL, Bergalet J, Lefebvre FA, Diot C, Wang X, Blanchette M. and Lécuyer E. CeFra-seq reveals broad asymmetric mRNA and non-coding RNA distribution profiles in Drosophila and human cells. (2017) [Epub ahead of print)

ENCODE Phase III: Building an encyclopedia of candidate regulatory elements for human and mouse. Nature. Submitted

Fabio A. Lefebvre and Eric Lécuyer. Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication. (2017), Front Microbiol.; Volume 8, Article 377

Fabio Alexis Lefebvre, Louis Philip Benoit Bouvrette, Julie Bergalet and Eric Lécuyer. Data for the generation of RNA spatiotemporal distributions and interpretation of Chk1 and SLBP protein depletion phenotypes during Drosophila embryogenesis. Data Brief (2017) 13: 28–31.

Kowanda, M. Bergalet, J., Wieczorek, M., Brouhard, G., Lécuyer, E., and Lasko, P.(2016). Loss of function of the Drosophila Ninein-relatedcentrosomal protein Bsg25D causes mitotic defects and impairs embryonic development. Biology Open. 5(8): 1040-1051.

Lefebvre FA, Bouvrette LP, Perras L, Blanchet-Cohen A, Garnier D, Rak J,Lécuyer E. (2016). Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation. Scientific Reports. 6:27680.

Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, Wei X, Van Nostrand EL, Huelga SC, Smalec BM, Wang X, Hong EL, Davidson JM,Lecuyer E, Graveley BR, Yeo GW. (2016). Resources for the comprehensive discovery of functional RNA elements. Molecular Cell. 61(6):903-13.

Gerby B., Tremblay C.S., Tremblay M., Rojas-Sutterlin S., Hébert J., Sauvageau G., Lemieux S., Lécuyer E., Veiga D.F.T. and Hoang T. (2014). SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. PLoS Genetics. 10: e1004768.

Iampietro, C., Bergalet, J., Wang, X., Cody, N.A., Chin, A., Lefebvre, F.A., Douziech, M., Krause, H.M., and Lécuyer, E. 2014. Developmentally-regulated elimination of damaged nuclei via a Chk2-dependent mechanism of mRNA nuclear retention. Developmental Cell, 29(4):468-81

Rojas-Sutterlin, S., Lécuyer, E., Hoang, T. 2014. Kit and Scl regulation of hematopoietic stem cells. Current Opinion in Hematology, 21(4), p 256–264.

Bergalet, J. and Lécuyer, E. 2014. The functions and regulatory principles of mRNA intracellular trafficking. In book on 'Systems and molecular perspectives to RNA binding protein biology' Edited by Gene Yeo. Adv Exp Med Biol, 825:57-96.

Bergalet, J., Iampietro, C., Chin, A., Oré-Rodriguez, S., Nguyen, X.-T., Cody, N.A., and Lécuyer, E. 2014. High-resolutions FISH procedures in Drosophila. In book on 'In situ hybridization methods' edited by Giselbert Hauptmann. Neuromethods. 714:31-47.

Cody, N.A., Iampietro, C., and Lécuyer, E. 2013. The many functions of mRNA localization during normal development and disease: from pillar to post. WIREs Dev Biol 2:781-96.

Zhang, Y,, Ponty, Y., Blanchette, M., Lécuyer, E., and Waldispühl, J. 2013. SPARCS: a web server to analyze (un)structured regions in coding RNA sequences. Nucleic Acids Res 41(Web Server issue):W480-5.

Legendre F, Cody N, Iampietro C, Bergalet J, Lefebvre FA, Moquin-Beaudry G, Zhang O, Wang X, and Lécuyer E. 2013. Whole mount RNA fluorescent in situ hybridization of Drosophila embryos. J Vis Exp 71, e50057.

Wang, E.T., Cody, N.A., Jog, S., Biancollela, M., Wang, T.T., Treacy, D.J., Luo, S., Schroth, G.P., Housman, D.E., Reddy, S., Lécuyer, E., and Burge, C.B. 2012. Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins. Cell  150:710-24.

Lécuyer, E. 2011. High resolution fluorescent in situ hybridization in Drosophila. Methods in Molecular Biology 714: 31-47. Edited by J. E. Gerst, Humana Press Inc.

Lécuyer, E., Yoshida, H., and Krause, H.M. 2009. Global implications of mRNA localisation pathways in cellular organisation. Curr Opin Cell Biol 3, 409-15.

Lécuyer, E., Nećakov, A.S., Cáceres, L. and Krause, H.M. 2008. High-resolution fluorescent in situ hybridization of Drosophila embryos and tissues. CSH Protocols, doi:10.1101/pdb.prot5019.

Lécuyer, E., Parthasarathy, N., and Krause, H.M. 2008. Fluorescent in situ hybridization protocols in Drosophila embryos and tissues. Methods in Molecular Biology 420: 289-302. Edited by C. Dahmann, Humana Press Inc.

Lécuyer, E., and Tomancak, P. 2008. Mapping the gene expression universe. Curr Opin Genet Dev 6, 506-12. 

Lécuyer, E. 2008. Le code de localisation des ARNm se révèle. Med. Sci. (Paris) 24, 350-1.

Lécuyer, E., Yoshida, H., Parthasarathy, N., Alm, C., Babak, T., Cerovina, T., Hughes, T.R., Tomancak, P., and Krause, H. M. 2007. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell 131, 174-87.


OTHER PUBLICATIONS

Lécuyer, E., Larivière, S., Sincennes, M.-C., Haman, A., Lahlil, R., Todorova, M., Tremblay, M., Wilkes, B.C., and Hoang, T. 2007. Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction. J. Biol. Chem. 282, 33649-58.

Lahlil, R.*, Lécuyer, E.*, Herblot, S., and Hoang, T. 2004. SCL assembles a multifactorial complex that determines glycophorin A gene expression. Mol. Cell. Biol. 24, 1439-52. *= Equal contribution by these authors.

Lécuyer, E., and Hoang, T. 2004. SCL: from the origin of hematopoiesis to stem cells and leukemia. Exp. Hematol. 32, 11-24. 

Tremblay, M., Herblot, S., Lécuyer, E., and Hoang, T. 2003. Regulation of pT alpha gene expression by a dosage of E2A, HEB and SCL. J. Biol. Chem. 278, 12680-7. 

Lécuyer, E., Herblot, S., St-Denis, M., Martin, R., Begley, C.G., Porcher, C., Orkin, S.H., and Hoang, T. 2002. The SCL-complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1. Blood 100, 2430-40.

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