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Research unit director
Publications
* These authors contributed equally to this work.
$ Both these authors act as corresponding authors

2014

Shahbabian, K., Jeronimo, C., Forget, A., Robert F. and Chartrand, P. (2014) Co-transcriptional recruitment of Puf6 by She2 couples translational repression to mRNA localization. Nucleic Acids Res. Jul 10. (Epub ahead of Print)

Coulombe, C., Poitras, C., Nordell-Markovits, A., Brunelle, M., Lavoie, M.A., Robert, F$. and Jacques, P.E.$ (2014) VAP : a versatile aggregate profiler for efficient genome-wide data representation and discovery. Nucleic Acids Res. 42 (Web Server issue):W485-93.

Jeronimo, C. and Robert, F (2014) Kin28 regulates the transient association of Mediator with core promoters. Nat Struct Mol Biol., 21 (5):449-55.

2013

Praktiknjo, S.D., Llamas, B., Scott-Boyer, M.P., Picard, S., Robert, F., Langlais, D., Haibe-Kains, B., Faubert, D., Silversides, D.W. and Deschepper, C.F. (2013) Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology, 154(12):4746-56.

Jeronimo, C., Bataille, A.R. and Robert, F (2013) The Writers, Readers, and Functions of the RNA Polymerase II C-Terminal Domain Code. Chem. Rev., 113(11):8491-522.

Woo, S., Zhang, X., Sauteraud, R., Robert, F. and Gottardo R. (2013) PING 2.0: An R/Bioconductor package for nucleosome positioning using next-generation sequencing data. Bioinformatics, 29(16):2049-50.

2012

Sansó, M., Lee, K.M., Viladevall, L., Jacques, P.É., Pagé, V., Nagy, S., Racine, A., St Amour, C.V., Zhang, C., Shokat, K.M., Schwer, B., Robert, F., Fisher, R.P., Tanny, J.C. (2012) A Positive Feedback Loop Links Opposing Functions of P-TEFb/Cdk9 and Histone H2B Ubiquitylation to Regulate Transcript Elongation in Fission Yeast. PLoS Genet., 8(8):e1002822.

Soontorngun, N., Baramee, S., Tangsombatvichit, C., Thepnok, P., Cheevadhanarak, S., Robert, F., Turcotte, B. (2012) Genome-wide location analysis reveals an important overlap between the targets of the yeast transcriptional regulators Rds2 and Adr1. Biochem. Biophys. Res. Commun. 423(4):632-7.

Bataille, A.R.*, Jeronimo, C.*, Jacques, P.E., Laramée, L., Fortin, M.-E., Forest, A., Bergeron, M., Hanes, S.D. and Robert, F. (2012) A Universal RNA Polymerase II CTD Cycle Is Orchestrated by Complex Interplays between Kinase, Phosphatase, and Isomerase Enzymes along Genes. Mol. Cell, 45:158-170.

2011

Poschmann, J., Drouin, S., Jacques, P.E., El Fadili, K., Newmarch, M., Robert, F., Ramotar, D. (2011) The Peptidyl Prolyl Isomerase Rrd1 Regulates the Elongation of RNA Polymerase II during Transcriptional Stresses. PLoS One, 6(8):e23159.

Gonsalves, S.E., Moses, A.M., Razak, Z., Robert, F., Westwood, J.T. (2011) Whole-Genome analysis reveals that active heat shock factor binding sites are mostly associated with non-heat shock genes in Drosophila melanogaster. PLoS One, 6(1):e15934.

Ivanovska, I., Jacques, P.É., Rando, O.J., Robert, F., Winston, F. (2011) Control of chromatin structure by spt6: different consequences in coding and regulatory regions. Mol Cell Biol, 31(3):531-541.

2010

Drouin, S., Laramée, L.*, Jacques, P.E.*, Forest, A., Bergeron, M., Robert, F. (2010) DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes. PLoS Genet, 6(10):e1001173, 1-12.

Hardy, S., Robert, F. (2010) Random deposition of histone variants: A cellular mistake or a novel regulatory mechanism? Epigenetics. 5(5).

2009

Szilard, R.K.*, Jacques, P.E.*, Laramée, L., Cheng, B., Galicia, S., Bataille, A.R., Yeung, M., Mendez, M., Bergeron, M., Robert, F$. and Durocher, D$. (2009) Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat Struct Mol Biol. 17(3):299-305.

Hardy, S.*, Jacques, P.-E.*, Gévry, N., Forest, A., Fortin, M.-È., Laflamme, L., Gaudreau, L. and Robert, F. (2009) The Euchromatic and Heterochromatic Landscapes Are Shaped by Antagonizing Effects of Transcription on H2A.Z Deposition. PLoS Genetics 5(10), e1000687.

Ghazal, G., Gagnon, J., Jacques, P.-E., Landry, J.-R., Robert, F. and Abou Elele, S. (2009) Yeast RNase III Triggers Polyadenylation-Independent Transcription Termination. Mol. Cell 36, 99-109.

Turcotte, B., Liang, X.B., Robert, F. and Soontorngun, N. (2009) Transcriptional regulation of nonfermentable carbon utilization in budding yeast. FEMS Yeast Res. Epub ahead of print.

Gévry, N., Hardy, S., Jacques, P.E., Laflamme, L., Svotelis, A., Robert, F., Gaudreau, L. (2009) Histone H2A.Z is essential for estrogen receptor signaling. Genes Dev 23:1522-1533.

Bataille, A.R. and Robert, F. (2009) Profiling genome-wide histone modifications and variants by ChIP-chip on tiling microarrays in S. cerevisiae. Methods Mol Biol 543, 267-279.

2008

Znaidi, S., Weber, S., Osman Zin Al-Abdin, O.Z., Bomme, P., Saidane, S., Drouin, S., Lemieux, S., De Deken, X., Robert, F. and Raymond, M. (2008) Genomewide Location Analysis of Candida albicans Upc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance. Eukaryot Cell 7(5), 836-47.

Truscott, M., Harada, R., Vadnais, C., Robert, F. and Nepveu, A. (2008) p110 CUX1 Cooperates with E2F Transcription Factors in the Transcriptional Activation of Cell Cycle-Regulated Genes. Mol. Cell. Biol. 28(10), 3127-38.

2007

Harada, R., Vadnais, C., Sansregret, L., Leduy, L., Bérubé, G., Robert, F. and Nepveu, A. (2007) Genome-Wide Location Analysis and Expression Studies Reveal a Role for p110 CUX1 in the Activation of DNA Replication Genes. Nucleic Acids Res. 36(1), 189-202.

Soontorngun, N., Larochelle, M., Drouin, S., Robert, F. and Turcotte, B. (2007) Regulation of gluconeogenesis in Saccharomyces cerevisiae is mediated by activator and repressor functions of Rds2. Mol. Cell. Biol. 27(22), 7895-7905.

Rufiange, A.*, Jacques, P-E.*, Bhat, W., Robert, F. and Nourani, A. (2007) Genome-Wide Replication-Independent Histone H3 Exchange Occurs Predominantly at Promoters and Implicates H3 K56 Acetylation and Asf1. Mol. Cell 27, 393-405.

Sonoda, J., Laganière, J., Mehl, I.R., Barish, G.D., Chong, L-W., Li, X., Scheffler, I.E., Mock, D.C., Bataille, A.R., Robert, F., Lee, C-H., Giguère, V., Evans, R.M. (2007) Nuclear receptor ERalpha and coactivator PGC1-beta are effectors of IFN-gamma-induced host defence. Genes Dev. 21, 1909-1920

Ferretti, V.*, Poitras, C*., Bergeron, D., Coulombe, B., Robert, F. and Blanchette, M. (2007) PReMod: A Database of genome-wide mammalian cis-regulatory module predictions. Nucleic Acids Res. 35(Database issue):D122-6.

2006

Larochelle, M.*, Drouin, S*., Robert, F. and Turcotte, B. (2006) Oxidative Stress-Activated Zinc Cluster Protein Stb5 Has Dual Activator/Repressor Functions Required for Pentose Phosphate Pathway Regulation and NADPH Production. Mol. Cell. Biol. 26(17), 6690-6701.     

Blanchette, M.$, Bataille, A.R., Chen, X., Poitras, C., Laganière, J., Lefèbvre, C., Deblois, G., Giguère, V., Ferretti, V., Bergeron, D., Coulombe, B. and Robert, F$. (2006) Genome-wide Computational Prediction of Transcriptional Regulatory Modules Reveals New Insights into Human Gene Expression. Genome Research 16, 656-668. PReMod (Accompanying database)

Nourani, A., Robert, F. and Winston, F. (2006) Evidence that Spt2/Sin1, an HMG-like Factor, Plays Roles in Transcription Elongation, Chromatin Structure, and Genome Stability in Saccharomyces cerevisiae. Mol. Cell. Biol. 26(4), 1496-1509.

2005

Guillemette, B.*, Bataille, A.*, Gévry, N., Adam, M., Blanchette, Robert, F$. and Gaudreau, L$. (2005) Variant Histone H2A.Z is Globally Localized to the Promoters of Inactive Yeast Genes and Regulates Nucleosome Positioning. PLoS Biology 3(12), e384.

Laganière, J., Deblois, G., Lefebvre, C., Bataille, A.R., Robert, F. and Giguère, V. (2005) Location Analysis of Estrogen Receptor alpha Target Promoters Reveals that FOXA1 Defines a Domain of the Estrogen Response. Proc. Natl. Acad. Sci. USA 102, 11651-11656.

prior to 2005

Robert, F.*, Pokholok, D.K.*, Hannett, N.M., Rinaldi, N.J., Chandy, M., Rolfe, A., Workman, J.L., Gifford, D.K., Young, R.A. (2004) Global Position and Recruitment of HATs and HDACs in the Yeast Genome. Mol Cell 16, 199-209.

Bar-Joseph, Z., Gerber, G.K., Rinaldi, N.J., Lee, T.I., Harbison, C.T., Robert, F., Gordon, D.B., Fraenkel, E., Simon, I., Jaakkola, T.S., Young, R.A. and Gifford, D.K. (2003) Computational discovery of gene modules and regulatory networks. Nature Biotechnology 21, 1337-1342.

Ng, H.H.*, Robert, F.*, Young, R., A. and Struhl, K (2003) Localized marking of active Pol II genes targeted recruitment of Set1 histone methylase provides a memory of recent transcriptional activity. Mol Cell 11, 709-19.

Lee, T. I.*, Rinaldi, N.J.*, Robert, F.*, Odom, D.T., Bar-Joseph, Z., Gerber, G.K., Hannett, N.M., Harbison, C.T., Thompson, C.M., Simon, I., Zeitlinger, J., Jennings, E.G., Murray, H.L., Gordon, D.B., Ren, B., Wyrick, J.J., Tagne, J-B, Volkert, T.L., Fraenkel, E., Gifford, D.K., Young, R.A. (2002) Transcriptional Regulatory Networks in Saccharomyces cerevisiae. Science 298, 799-804.

Ng, H.H.*, Robert, F.*, Young, R., A. and Struhl, K (2002) Genome-wide Location and Regulated Recruitment of the RSC nucleosome-remodeling complex. Genes Dev. 16, 806-819.

Robert, F., Blanchette, M., Maes, O., Chabot, B. and Coulombe, B. (2002) A human RNA polymerase II-containing complex associated with factors necessary for spliceosome assembly. J. Biol. Chem. 277, 9302-9306.

Adam, M.*, Robert, F.*, Larochelle, M.* and Gaudreau, L. (2001) H2A.Z is Required for Global Chromatin Integrity and for Recruitment of RNA Polymerase II under Specific Conditions. Mol. Cell. Biol. 21, 6270-6279.

Ren, B.*, Robert, F.*, Wyrick, J. J.*, Aparicio, O., Jennings, E. G., Simon, I., Zeitlinger, J., Schreiber, J., Hannett, N., Kanin, E., Volkert, T. L., Wilson, C. J., Bell, S. P. and Young, R. A. (2000) Genome-wide Location and Function of DNA Binding Proteins. Science, 290, 2306-2309.

Robert, F. and Coulombe, B. Methods in Molecular Biology 2nd edition: The use of site-specific protein-DNA photo-crosslinking to analyse the molecular organization of the RNA polymerase II initiation complex (Hunana Press, Totowa, NJ, USA).

Robert, F., Douziech, M., Forget, D., Elgy, J-M., Greenblatt, J., Burton, Z. F. and Coulombe, B. (1998) Wrapping of Promoter DNA around the RNA Polymerase II Initiation Complex Induced by TFIIF. Mol. Cell 2, 341-351.

Forget, D., Robert, F., Grondin, G., Burton, Z. F., Greenblatt, J. and Coulombe, B. (1997) RAP74 Induces Promoter Contacts by RNA Polymerase II Upstream and Downstream of a DNA Bend Centered on the TATA box. Proc. Natl. Acad. Sci. USA 94, 7150-7155.

Robert, F., Forget, D., Li, J., Greenblatt, J. and Coulombe, B. (1996) Localization of Subunits of Transcription Factors IIE and IIF Immediately Upstream of the Transcription Initiation Site of the Adenovirus Major Late Promoter. J. Biol. Chem. 271(5), 8517-8520.

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