Jacques Archambault, PhD
Dr. Archambault’s research focus is the molecular biology of human papilloma viruses (HPV), a group of viruses with DNA that causes benign and malignant lesions of the skin and mucous membranes. HPV infections are among the most prevalent sexually transmitted diseases, and infections by certain oncogenic HPV types are the cause of cervical cancer, the second most common cancer affecting women worldwide.
His laboratory uses molecular and cellular biology approaches as well as biochemical and biophysical methods to shed light on how the viral genome is maintained and replicated in infected cells. Functional genomics and proteomics approaches are also used to identify cellular factors targeted by HPV proteins and learn more about the roles they play in the viral cycle and pathogenesis. High-throughput screening of collections of chemical compounds is also used to identify small molecules with antiviral and anticancer properties. These studies will lead to new approaches to the treatment of HPV-related infections and cancers.
Degrees and relevant experience