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Home > Molecular Virology > Publications
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Mesplède T, D Gagnon, F Bergeron-Labrecque, I Azar, H Sénéchal, F Coutlée and J Archambault. 2011. P53-degradation Activity, Expression and Subcellular Localization of E6 Proteins from 29 Human Papillomavirus Genotypes.J Virol, in press.

D’Abramo, C M, A Fradet-Turcotte, and J Archambault. 2011. Human papillomavirus DNA replication: Insights into the structure and regulation of a eukaryotic DNA replisome. In "Small DNA Tumour Viruses", Ed. Kevin Gaston, Horizon Scientific Press, p.217-239. (Book chapter)

Fradet-Turcotte A., F Bergeron-Labrecque, CA Moody, M Lehoux, L A Laimins and J Archambault. 2011. Nuclear Accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response. J Virol, 85:8996-9012.

D’Abramo CM and J Archambault. 2011. Small Molecule Inhibitors of Human Papillomavirus Protein-Protein Interactions. Open Virol J, 5:80-95. (Invited review)

Meinke G, P Phelan, A Fradet-Turcotte, J Archambault and PA Bullock. 2011. Structure-based design of a disulfide-linked oligomeric form of the Simian Virus 40 (SV40) large T antigen DNA binding domain. Acta Crystallogr D Biol Crystallogr. 67:560-567.

Morin G, A Fradet-Turcotte, P Di Lello, F Bergeron-Labrecque, JG Omichinski and J Archambault. 2011. A conserved amphipathic helix in the N-terminal regulatory region of the papillomavirus E1 helicase is required for efficient viral DNA replication. J Virol, 85:5287-5300.

Meinke G, PJ Phelan, A Fradet-Turcotte, A Bohm, J Archambault and PA Bullock. 2011. Structure-based analysis of the interaction between SV40 T-antigen origin binding domain and single-stranded DNA. J Virol, 85:818-827.

Fradet-Turcotte A, C Moody, LA Laimins, J Archambault. 2010. Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance.J Virol, 84:11747-11760.

Fradet-Turcotte A, G Morin, M Lehoux, PA Bullock, J Archambault. 2010. Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replication. Virology, 399: 65-76.

Domecq C, M Kireeva, J Archambault, M Kashlev, B Coulombe B, ZF Burton. 2010. Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II. Protein Expr Purif, 69:83-90.

Fradet-Turcotte A, K Brault, S Titolo, PM Howley, J Archambault. 2009. Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9. Virology, 395:190-201.

Lehoux M, CM D’Abramo, J Archambault (Review). 2009. Molecular mechanisms of HPV-induced carcinogenesis (Review). Public Health Genomics 12:268-280.

Gagnon D, S Joubert, H Sénéchal, A Fradet-Turcotte, S Torre, J Archambault. 2009. Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of the bromodomain-containing protein 4 (Brd4). J Virol, 83:4127-4139.

Côté-Martin A, C Moody, A Fradet-Turcotte, CM D'Abramo, M Lehoux, S Joubert, GG Poirier, B Coulombe, LA Laimins, J Archambault. 2008. The human papillomavirus E1 Helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes. J Virol, 82:1271-1283.

Domecq C, V Trinh, MF Langelier, J Archambault, B. Coulombe. 2008. Inhibitors of multisubunit RNA polymerases as tools to study transcriptional mechanisms in prokaryotes and eukaryotes (Review). Curr Chem Biol, 2:20-31.

Di Lello P, LM Miller Jenkins, C Mas, C Langlois, E Malitskaya, A Fradet-Turcotte, J Archambault, P Legault, JG Omichinski. 2008. p53 and TFIIE alpha share a common binding site on the Tfb1/p62 subunit of TFIIH. Proc Natl Acad Sci (USA), 105:106-111.

Moody CA, A Fradet-Turcotte, J Archambault, LA Laimins. 2007. Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification. Proc Natl Acad Sci (USA), 104:19541-19546.

Fradet-Turcotte A, J Archambault. 2007. Recent advances in the search for antiviral agents against human papillomaviruses (Review). Antivir Ther, 12:431-451.

Fradet-Turcotte A, C Vincent, S Joubert, PA Bullock, J Archambault. 2007. Quantitative analysis of the binding of simian virus 40 large T antigen to DNA. J Virol, 81:9162-9174.

Kumar A, G Meinke , DK Reese, S Moine, PJ Phelan, A Fradet-Turcotte, J Archambault, A Bohm, PA Bullock. 2007. Model for T-antigen-dependent melting of the simian virus 40 core origin based on studies of the interaction of the beta-hairpin with DNA. J Virol, 81:4808-4818.

Sénéchal H, GG Poirier, B Coulombe, LA Laimins, J Archambault. 2007. Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4. Virology, 358:10-17.

Trinh V, MF Langelier, J Archambault, B Coulombe. 2006. A structural perspective on amino acid substitutions affecting the function of multisubunit RNA polymerases (Review). Microbiol Mol Biol Rev, 70:12-36.

White PW, AM Faucher, MJ Massariol, E Welchner, J Rancourt , M Cartier, J Archambault. 2005. Biphenylsulfonacetic acid inhibitors of the human papillomavirus type 6 E1 helicase inhibit ATP hydrolysis by an allosteric mechanism involving tyrosine 486. Antimicrob Agents Chemother, 49:4834-4842.

Langelier MF, D Baali, V Trinh, J Greenblatt, J Archambault, B Coulombe. 2005. The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II. Nucleic Acids Res, 33:2629-2639.

Abbott KL, J Archambault, H Xiao, BD Nguyen, RG Roeder, J Greenblatt, JG Omichinski, P Legault. 2005. Interactions of the HIV-1 Tat and RAP74 Proteins with the RNA polymerase II CTD Phosphatase FCP1. Biochemistry, 44: 2716-2731.

Davidson W, GA McGibbon, PW White, C Yoakim, JL Hopkins, I Guse, DM Hambly, L Frego, WW Ogilvie, P Lavallée, J Archambault. 2004. Characterization of the Binding Site for Inhibitors of the HPV11 E1-E2 Protein Interaction on the E2 Transactivation Domain by Photoaffinity Labeling and Mass Spectrometry. Anal Chem, 76:2095-2102.

Wang Y, R Coulombe, D Cameron, L Thauvette, M-J Massariol, LM Amon, D Fink, S Titolo, E Welchner, C Yoakim, J Archambault, PW White. 2004. Crystal Structure of the E2 Transactivation Domain of Human Papillomavirus Type 11 Bound to a Protein Interaction Inhibitor. J Biol Chem, 279:6976-6985.

White PW, S Titolo, K Brault, L Thauvette, A Pelletier, E Welchner, L Bourgon, L Doyon, WW Ogilvie, C Yoakim, MG Cordingley, J Archambault. 2003. Inhibition of human papillomavirus DNA replication by small molecule antagonists of the E1-E2 protein-protein interaction. J Biol Chem, 278:26765-26772.

Yoakim C, WW Ogilvie, N Goudreau, J Naud, B Haché, JA O’Meara, MG Cordingley, J Archambault, PW White. 2003. Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1-E2-origin DNA complex. Bioorg Med Chem Lett, 13:2539-2541.

Nguyen BD, K Abbott, K Potempa, MS Kobor, J Archambault, Greenblatt, P Legault, JG Omichinski. 2003. NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAPII CTD Phosphatase FCP1. Proc Natl Acad Sci (USA), 100:5688-5693.

Titolo S, E Welchner, PW White, J Archambault. 2003. Characterization of the DNA-binding properties of the origin-binding domain of SV40 Large T Antigen by fluorescence anisotropy. J Virol, 77:5512-5518.

Titolo, S, K Brault, J Majewski, PW White, J Archambault. 2003. Characterization of the minimal DNA binding domain of the human papillomavirus E1 helicase: Fluorescence anisotropy studies and characterization of a dimerization-defective mutant protein. J Virol, 77:5178-5191.

White PW, A Pelletier, K Brault, S Titolo, E Welchner, L Thauvette, M Fazekas, MG Cordingley, J Archambault. 2001. Characterization of recombinant HPV6 and 11 E1 helicases. Effect of ATP on the interaction of E1 with E2 and mapping of a minimal helicase domain. J Biol Chem, 276:22426-22438.

Kobor MS, L Simon, J Omichinski, J Archambault, J. Greenblatt. 2000. A motif shared by TFIIF and TFIIB mediates their interaction with the RNA polymerase II CTD phosphatase in S. cerevisiae. Mol Cell Biol, 20:7438-7449.

Titolo S, A Pelletier, AM Pulichino, K Brault, E Wardrop, PW White, MG Cordingley, J Archambault. 2000. Identification of domains of the human papilloma virus type 11 E1 helicase involved in oligomerization and binding to the viral origin. J Virol, 74:7349-7361.

Amin AA, S Titolo, A Pelletier, D Fink, MG Cordingley, J Archambault. 2000. Identification of domains of the HPV11 protein required for DNA replication in vitro. Virology, 272:137-150.

Kobor M, J Archambault, W Lester, FC Holstege, O Gileadi, DB Jansma, EG Jennings, F Kouyoumdjian, AR Davidson, RA Young, J Greenblatt. 1999. An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae. Mol Cell, 4:55-62.

Titolo S, A Pelletier, F Sauvé, K Brault, E Wardrop, PW White, A Amin, MG Cordingley, J Archambault. 1999. Role of the ATP-binding domain of the human papillomavirus type 11 E1 helicase in E2-dependent binding to the origin. J Virol, 73:5282-5293.

Archambault J, G Pan, GK Dahmus, M Cartier, N Marshall, S Zhang, ME Dahmus, J Greenblatt. 1998. FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO. J Biol Chem, 273:27593-27601.

Archambault J, DB Jansma, JH Kawasoe, KT Arndt, J Greenblatt, JD Friesen. 1998. Stimulation of transcription by mutations affecting conserved regions of RNA polymerase II. J Bacteriol, 180:2590-2598.

Archambault J, RS Chambers, MS Kobor, Y Ho, M Cartier, D Bolotin, B Andrews, CM Kane, J Greenblatt. 1997. An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharamyces cerevisiae. Proc Natl Acad Sci (USA), 94:14300-14305.

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