This research unit is interested in signal transduction mechanisms in the immune and hematopoietic systems. Over the past decade, Dr. Veillette’s team has identified and characterized numerous intracellular molecules that play a crucial role in normal cell physiology. A number of these molecules are directly or indirectly involved the pathogenesis of leukemias, lymphomas and other malignancies. They have also been linked to the development of certain immunodeficiencies. These proteins are potential targets in therapeutic immunosuppression for the treatment of autoimmune diseases and graft rejection. The team uses novel molecular, biochemical and cellular approaches to study these molecules.
Discovery of a control mechanism against cancer and infections. A Forum en clips video from the Université de Montréal discussing a scientific breakthrough made by Dr. André Veillette and his team. Length: 2:41 (In French only)