Research papers

Campo VA, Patenaude AM, Kaden S, Horb L, Firka D,Jiricny J and Di Noia JM. MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils. Nucl. Acids Res. 2013 doi: 10.1093/nar/gks1470 [open access].

Hu Y, Ericsson I, Torseth K, Methot SP, Sundheim O, Liabakk NB, Slupphaug G, Di Noia JM, Krokan HE, Kavli B. A Combined Nuclear and Nucleolar Localization Motif in Activation-Induced Cytidine Deaminase (AID) Controls Immunoglobulin Class Switching. J Mol Biol.  2013; 425:424-43. doi: 10.1016/j.jmb.2012.11.026. Epub 2012 Nov 23.

Orthwein A, Zahn A, Methot S, Godin D, Conticello SG, Terada K and Di Noia JM. Optimal functional levels of Activation Induced Deaminase specifically require the Hsp40 DnaJa1. EMBO J 2011; 31: 679-91.

De Marchi, CR; Di Noia, JM; Frasch, AC; Amato Neto, V; Almeida, IC; Buscaglia, CA. Evaluation of a Recombinant Trypanosoma cruzi Mucin-Like Antigen for Serodiagnosis of Chagas' Disease. Clin. Vaccine Immunol 2011; 18:1850-5.

Orthwein A, Patenaude A-M, Affar E-B, Lamarre A, Young JC and Di Noia, JM. Regulation of Activation Induced Deaminase stability and antibody gene diversification by Hsp90. J Exp Med 2010; 207:2751-2765.

Patenaude A-M, Orthwein, A, Yi Hu, Campo, VA, Kavli, B, Buschiazzo, A and Di Noia, JM. Nuclear import and cytoplasmic retention of Activation Induced Deaminase. Nat Struct Mol Biol 2009; 16:517-27.

Reviews

Orthwein, A and Di Noia, JM. AID: How much and where?.Semin Immunol, 2012; 24:246-254.

Orthwein, A and Di Noia, JM. Moduler la diversification des anticorps pour combattre certaines maladies. Médecine Sciences Amérique; 1(2), April 15th, 2012 (online journal in French).

Patenaude A-M and Di Noia, JM. The mechanisms regulating the subcellular localization of AID. Nucleus. 2010; 1(4):325-331.

Di Noia JM, Neuberger MS. Molecular mechanisms of antibody somatic hypermutation. Ann Rev Biochem, 2007; 76:1-22.

Book chapters
Ramiro, A and Di Noia, JM. Regulatory mechanisms of AID function. In: DNA Deamination and the Immune System. S Fungmann, M Diaz & FN Papavasiliou Eds. Imperial College Press, London, UK. 2010. in press.