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Conferences

2017

Invited Speaker: “The biology and functions of the proprotein convertases PCSK9 & PCSK7”. International Proteolysis Society (IPS2017); Banff, Alberta, Canada; October 28 - November 2, 2017. http://www.ips2017.org/

Invited Speaker: “What regulates the sorting of the PCSK9-LDLR complex to endosomes/lysosomes”. 38th Steenbock Symposium on “Protein Trafficking in the Secretory Pathway”. University of Wisconsin-Madison, Madison, WI, USA; June 22-25, 2017. https://biochem.wisc.edu/symposia/steenbock/38th

Invited Speaker: “The sex/tissue-specific regulation of the LDLR in absence of PCSK9 activity and its clinical relevance”. OSSD Montreal, Hyatt Regency hotel, Quebec May15, 2017 http://www.ossdweb.org/ossd-2017

Special Lecture: “The implication of PCSK9 in cardiometabolic disorders”. 81st Annual Scientific meeting of the Japanese Circulation Society (JCS), Kanazawa, Japan; March 17-19, 2017.
http://www.j-circ.or.jp/english/scientific_sessions/81th_jcs2017.pdf

2016

Plenary Lecture: “The saga of PCSK9, and its LDL regulation: from bench to bedside”. 21th Annual Meeting of the Israeli Society for Research, Prevention and Treatment of Atherosclerosis. Haifa, Israel, October 27-30, 2016. http://www.israel-heart.org.il/images/pdf/prog1.pdf

Invited Speaker: "What does the study of the PCSK9 biology tell us about its functions?” Canadian Society of Atherosclerosis Thrombosis and Vascular Biology (CSATVB). Special Jean Davignon Symposium on PCSK9, Cholesterol Metabolism and CVD. Montreal, October 23rd lecture. Meeting October 22-25. http://www.csatvb.ca/conferences

Invited Speaker: "Les proprotéines convertases et leurs multiples fonctions en neuroendocrinologie". Mécanismes qui régulent la secretion neuroendocrine, congrès de la Société de Neuroendocrinologie (SNE). Corte, Corsica, France, October 5-8, 2016. http://sne-corte2016.sciencesconf.org/

Plenary Lecture: “The saga of PCSK9, an LDLR-regulating enzyme: from bench to bedside”. 5th International Congress on Lipid Metabolism & Atherosclerosis (ICLA 2016) and the 52th Fall Conference of the Korean Society of Lipidology & Atherosclerosis, Seoul, Korea; September 9-10, 2016. http://icla2016.org/scientific/plenary.php#pl2 

Invited Chairman and co-organizer: Protein Processing, Trafficking & Secretion. GRC  Colby Sawyer, NH; USA, July 24-29, 2016 https://www.grc.org/programs.aspx?id=12434

Invited Speaker: Plenary Lecture “The PCSK9 revolution in cholesterol reduction”. Toronto, May 14, 2016
https://www.eply.com/ClientFiles/Toronto%20Knowledge%20Translation%20Working%20Group-1386/Documents/2016PCSK9-Toronto.pdf

Invited Speaker: Plenary Lecture “The PCSK9 revolution in cholesterol reduction”. Montréal, March 18, 2016. https://www.eply.com/ClientFiles/Toronto%20Knowledge%20Translation%20Working%20Group-1386/Documents/v5PCSK9%20Montreal%202016%20AGENDA_LowRes%20r15.pdf

2015

Keynote Speaker: “The PCSK9 revolution: experience gained from its discovery to bedside clinical applications”. Chronic Disease Partner Forum, Ottawa, Canada, June 10-11, 2015 English: http://www.cihr-irsc.gc.ca/e/49437.html
Français : http://www.cihr-irsc.gc.ca/f/49437.html

Invited Speaker: Plenary Lecture. "The discovery of PCSK9: A Canadian legacy". Symposium on "The PCSK9 Revolution in Cholesterol Reduction". CHUM Montreal, QC, May 30th, 2015 https://www.eply.com/ClientFiles/Toronto%20Knowledge%20Translation%20Working%20Group-1386/Documents/PCSK9_Agenda_12.10.14.pdf

Invited Speaker: “The proprotein convertases and extracellular matrix remodeling”. Extracellular Matrix Biochemistry theme. American Society for Biochemistry and Molecular Biology, ASBMB, 2015 Annual Meeting. Meeting held in conjunction with Experimental Biology, Boston MA, March 20, 2015 http://www.asbmb.org/Search.aspx?s=Seidah

Invited Speaker: Plenary Lecture “The PCSK9 revolution: Cholesterol reduction and beyond”. Anne and Neil McArthur Award Event. Hamilton, ON, - Feb 25th, 2015 http://stjoesfoundation.ca/page.aspx?pid=463

2014

Plenary Lecture “PCSK9: a key modulator of cardiovascular health; a harbinger of the future”. Jacques Genest CSEM Award Lecture for the 17th Canadian Diabetes Association/CSEM Annual Meeting. Winnipeg, Manitoba, Canada, Oct. 23 to 26, 2014
https://www.diabetes.ca/getmedia/0b96f403-0b0c-4762-b772-73a0b68aa100/2014-cda-csem-program.aspx

Plenary Lecture “PCSK9: from discovery to clinical applications”. 9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress. Kyoto, Japan , Sept 11-14, 2014
http://www.congre.co.jp/msda2014/overview.html

Invited Keynote Speaker and organizer of the PCSK9 Session: “The proprotein convertases: from bench discovery to bedside clinical applications”. At the crossroads of understanding the maturation and transport of proteins/peptides and the therapeutic applications; GRC  Colby Sawyer, NH; July 20-25

Chairman and speaker: “Cellular and molecular mechanisms of PCSK9”. Mini-Symposium on Metabolic Disorders: their Rising Importance in the Age of Personalized Medicine. IRCM, Montreal April 24-25, 2014 http://www.ircm.qc.ca/CONFERENCES/METABOLIC/Pages/default.aspx?PFLG=1033
https://www.ircm.qc.ca/CONFERENCES/past/metabolic/Documents/CARDIOVASCULAR%20CONFERENCE%20PROGRAM-Final.pdf  

2013

Invited Speaker: “The obscure proprotein convertase PC7: Novel physiological functions in mouse and human”. 8th General Meeting of the International Proteolysis Society. Spier Conference Centre, Cape Town, South Africa, October 20-24, 2013 http://www.ips2013.org/programme.php

Invited Plenary Speaker for the Simon Pierre-Noël Memorial Lecture 2013: “The cellular and physiological functions of PCSK9 and clinical outcomes of its targeting”. The Canadian Lipoprotein Conference. September 26-29, 2013, Mont Tremblant, QC (Guest of Dr. Robert Scott Kiss). http://lipoprotein.ca/wp-content/uploads/CLC_Final_Program_Booklet.pdf

Invited Speaker: Plenary Lecture “La proprotéine convertase PCSK9: historique, biologie et applications cliniques”. GRAND ROUNDS CHUM, Montreal, QC, Sept. 11, 2013 Invited Speaker: PC5 and Furin in glioma invasion. 96th Canadian Chemistry Conference Quebec city, May 26-27, 2013. http://www.csc2013.ca/2_program/program_info.html
 
Invited Speaker: Colloque 55 - Le goût de faire de la science. Université Laval, Québec May 8, 2013
http://www.acfas.ca/evenements/congres/programme/81/600/55/c

Invited Speaker: “Novel functions of the secretory proprotein convertases: from neuroendocrine roles to the regulation of anxiety and cardiovascular diseases”. Neuroscience Institute and Morehouse School of Medicine - Atlanta, Georgia, April 12, 2013 (Guest of Dr. An Zhou)http://www.msm.edu/research/research_centersandinstitutes/NI.aspx 

Invited Speaker: “The obscure proprotein convertase PC7: unexpected physiological roles”. Beer Seminar series at the Meakins-Christie Laboratories. McGill University, Montreal, QC (Guest of Dr. William S. Powell), March 25, 2013 http://meakins.mcgill.ca/events/beer_seminars.php

2012

Proprotein Processing, Trafficking & Secretion. Chair: Lloyd D. Fricker Vice Chair: John W. Creemers. Gordon research Conference. Colby-Sawyer College New London, NH July 15-20, 2012 http://www.grc.org/programs.aspx?year=2012&program=proproc

Proteolysis: The Most Important Post Translational Modification Regulating Biology, Life and Death of Every Cell. Proteolytic Enzymes & Their Inhibitors. Chair: Klaudia Brix Vice Chair: James C. Whisstock. Il Ciocco Hotel and Resort Lucca (Barga), Italy June 17-22, 2012 http://www.grc.org/programs.aspx?year=2012&program=protenz

The various biological functions of the proprotein convertases and their implications in viral infections. Department of Microbiology & Immunology, Cornell University. Ithaca New York, April 23, 2012 http://instruct1.cit.cornell.edu/research/whittakerlab/

The physiological roles of PCSK9 and its targeting strategies for lipid lowering. Workshop on Novel lipid-lowering strategies. XVI International Symposium on Atherosclerosis. Sydney, Australia, March 25-29, 2012 http://www.isa2012.com/pdf/ISA2012_Program.pdf

The biology and pathophysiology of the proprotein convertases. Hemovascular Group at the Lady Davis Institute, Sir Mortimer B. Davis Jewish General Hospital. March 16, 2012  

2011

La  saga des proprotéines convertases: fonctions physiologiques et pathologiques. Journée Phare. Université de Sherbrooke, department de Pharmacologie. Hôtel Chéribourg, Magog, Québec, November 4, 2011 http://www.journeephare.com/

Novel insights into the physiological functions of the proprotein convertases. 7th General Meeting of the International Proteolysis Society. San Diego, California, October 16-20, 2011 http://www.ips2011.org/Speakers.html#seidah

Is reduction of PCSK9 levels a promising therapy for atherosclerosis?: in vivo models and novel approaches to silence PCSK9. National Atherosclerosis Forum. Montreal, October 13-14, 2011

Les proprotéines convertases et leurs implications pathologiques incluant le cancer et la métastase. FRSQ-INSERM, UMRS 940, Paris Sept. 28-Oct. 6, 2011

The implication of the proprotein convertases in health and diseases. Seminar, Duke University, Durham, NC, Sept. 20-22, 2011 http://calendar.duke.edu/events/index?user_date=09%2F21%2F2011

La nouvelle odyssée du cholesterol. Café scientifique, Montréal, Québec, June 14, 2011

Invited Speaker: “Les proprotéines convertases dans le cancer et la métastase : Nouvelles cibles thérapeutiques”. Programme Champlain 62.102; INSERM, UMRS 940, Paris May 13-21, 2011

The functional and translational biology of the proprotein convertases. Vascular Biology seminar series. Kidney Research Centre, Ottawa, March 23, 2011. http://www.ohri.ca/newsroom/seminars_short.asp?Program=Vascular

The proprotein convertases: multiple physiological functions and clinical implications. Institut for Cellulær og Molekylær Medicin, Københavns Universitet, Denmark, March 11-15, 2011 http://icmm.ku.dk/Forskergrupper/CCG/meetings/invited_speakers/

The roles of the proprotein convertases in the metabolic syndrome. Montreal Diabete Research center, 5th MDRC. Montreal, January 28, 2011

The proprotein convertases: 20 years later. Killam Seminar, MNI Montreal Jan 25, 2011 http://apps.mni.mcgill.ca/killam10.htm

PCSK9: from cellular and molecular biology to translational applications. Shifa Biomedical Corporation, Malvern, Pensylvannia. January 10, 2011


2010

PCSK9 and lipid metabolism. NAF National Atherosclerosis Forum, Montreal, Quebec, Sept. 30 – Oct 2, 2010 https://enaf.ca/

Discussion leader: Session - Proprotein convertases and cardiovascular disease. GRC of Proprotein Processing, Trafficking & Secretion. GRC on Proprotein Processing, Trafficking and Secretion, Colby-Sawyer College, New London, NH. July 18-23, 2010 GRC New London

Novel insights into the physiological functions of PCSK7. GRC of Proprotein Processing,
Trafficking & Secretion, Colby-Sawyer College, New London, NH. July 18-23, 2010 GRC New London

Keynote Speaker: Jacques Benoit Lecture The secretory proprotein convertases: critical
roles in the neuroendocrine axis & implications in pathophysiological disorders. International Society of Neuroendocrinology. Rouen, France. July 11-15, 2010 Jacques Benoit Lecture

Novel developments in our understanding of PCSK9 functions. Seminar at Bristol Myers Squibb , Princeton, NJ. May 12-13, 2010

Novel developments in our understanding of the PCSK9-enhanced degradation of the LDLR and other receptors. GRC of Proteolytic Enzymes & Their Inhibitors. Lucca (Barga), Toscona, Italy. May 2-7, 2010 GRC Italy

The proprotein convertases: from molecular and cell biology to in vivo functions and therapy. Seminar in Cell Biology. Jacobs University, Bremen, Germany. April 30, 2010 Seminar - Univ. Bremen

The proprotein convertases: from cellular functions to in vivo applications. Seminar in Biological Chemistry. University of Michigan Medical Center, Ann Arbor, MI. April 27, 2010 Seminar - Univ. Michigan

From cellular biology to physiological implications: a tale of two convertases. Retraite
scientifique des chercheurs de l’IRCM. Hôtel Estrimont, Orford, March 26, 2010 Retraite des chercheurs IRCM

Du cholestérol 101 aux dernières découvertes
. Scientific coffee. Montreal. March 22, 2010
Café scientifique

PCSK9-enhanced degradation of receptors: cellular pathways. PCSK9 Conference: from gene to therapeutics. Nantes, France. March 11-13, 2010 PCSK9 Conference

The proprotein convertases SKI-1/S1P and PCSK9: from cholesterol metabolism to viral infection. Merck Frosst. Montreal, QC, Canada. January 22, 2010


2009

Insights into the Function and Regulation of PCSK9. Deuel Conference on Lipids. La Casa Borrego Springs, CA. March 3 – 5, 2009 Deuel Conference

The proprotein convertases in health and disease. Department of Physiology and Biophysics, Dalhousie University Dalhousie Halifax. June 11-12, 2009 Seminar Univ Dalhousie

PCSK9 and cardiovascular diseases. Crossroad for BioTransfer 2009, University of Montreal. May 5, 2009

PCSK9 biology and clinical applications. Merck. Rahway New Jersey. July 15, 2009

Dissection of the PCSK9-induced degradation pathways of the LDLR. 11th National Atherosclerosis Forum. Montreal, Quebec, Canada. Sept. 25-26, 2009 National Atherosclerosis Forum

PCSK9 and Hepatitis C infection. IRCM lectures of the Cardiovascular and Metabolic Disease
axis. Montreal, Quebec, Canada. October 1st, 2009 Axe des maladies cardiovasculaires et métaboliques

Role of the proprotein convertases in viral infections. 8th ICAV Symposium. Corsica, France. October 2-7, 2009 International Consortium Antivirals

PCSK9: a proprotein convertase implicated in dyslipidemia. Canadian Lipoprotein Conference. Windsor, Ontario. October 15-18, 2009

The proprotein convertases: structure-function and in vivo functions. Structural Genomics Consortium. Toronto, November 10-11, 2009

La proprotéine convertase PCSK9: LDL-cholestérol et infections virale et parasitaire. Centre Hospitalier Universitaire Pitié-Salpêtrière. November 27, 2009

2008

The proprotein convertases and their roles in neuroendocrine dysfunctions.Wyeth Neuroscience Discovery, Princeton, January 28-29, 2008

The physiological and pathological functions of the proprotein convertases: emphasis on PCSK9. Rinat Neuroscience, Pfizer Global Research and Development, San Francisco, March 7, 2008

What did we learn so far from the in vitro and in vivo studies of the proprotein
convertases? Retraite scientifique des chercheurs de l’IRCM. Hôtel Mont-Gabriel, Ste-Adèle, April 17,18, 2008 Retraite Chercheurs IRCM

The Proprotein Convertases Affect Viral Infection in a Variety of Ways. ICAV Sixth
Symposium, Toronto, May 3 – 6, 2008 International Consortium Antivirals

The role PCSK9 in liver and gut. Bristol Myers Squibb, Princeton, NJ, May 7-8, 2008

The role the proprotein convertases in the homeostasis of cholesterol: emphasis on PCSK9.
Santaris Pharmaceuticals, Copenhagen, Denmark, May 25-27, 2008

Sterol regulation by the proprotein convertases. Zora Biosciences, Espoo, Finland, May
27-29, 2008

Furin, PC5/6 and PCSK9 in health and disease. GRC Lipoprotein Metabolism Waterville Valley, New Hampshire June 22-27, 2008 GRC Lipoprotein

Discussion leader: Session The Role of Proteolysis in Lipid metabolism. GRC on Proteolytic Enzymes and their Inhibitors, Colby-Sawyer College, New London, NH , July 6-11, 2008 GRC Proteolytic Enzymes and thier inhibitors

Implication of the proprotein convertases in cardiovascular disorders and beyond. GRC on Proteolytic Enzymes and their Inhibitors, Colby-Sawyer College, New London, NH, July 6-11, 2008 GRC Proteolytic Enzymes and thier inhibitors

Discussion leader: Session - Convertases in Dyslipidemia and PathogenInfections; Pathophysiology. GRC on Proprotein Processing, Trafficking and Secretion, Colby-Sawyer College, New London, NH, July 13-18, 2008 GRC New London (Proprotein Processing Trafficking and secretion)

Lessons from convertase knockout mice. GRC on Proprotein Processing, Trafficking and Secretion, Colby-Sawyer College, New London, NH, July 13-18, 2008 GRC New London

The proprotein convertases and dyslipidemia. 10th National Atherosclerosis Forum. Toronto.
Sept. 26-28, 2008 National Atherosclerosis Forum

The proprotein convertases in health and disease: from genotype to phenotype
. ISREC,
School of Life Sciences. Ecole Polytechnique Fédérale de Lausanne. Epalinges, Switzerland, Oct. 24 – 26, 2008 IRSEC Seminaire

The proprotein convertases in health and pathology : in vivo validation of a genetic correlation. 2nd Al-Ain International Genetics Conference Al-Ain, United Arab Emirates October 27-30 2008 Dubai: International Genetics Conference

Session Chairman: New Approaches to Drug Discovery
Avian Influenza – Science & Policy
International Consortium Antiviral (ICAV) Bejing, China, Nov 1- 7, 2008 International Consortium Antivirals

The proprotein convertase PCSK9 reduces the level of cell surface LDLR and CD81 and impedes Hepatitis C viral infection. International Consortium Antiviral (ICAV) Bejing, China. Nov 1- 7, 2008 International Consortium Antivirals

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