The IRCM
Research
The Clinic
Studying at IRCM
Core facilities
Conferences
Careers
Molecular Biology of Neural Development
Skip navigation links
Home
Director
Projects
Approaches and models
Publications
Charron Lab: In The News
Team
Lab Photos
Lab Alumni
Contact us


The IRCM > Research > Research divisions > Neurobiologie et développement > Biologie moléculaire du développement neuronal
Home > Molecular Biology of Neural Development
Home > Molecular Biology of Neural Development
Research unit director
Charron Lab 

The brain is composed of billions of neurons that form a complex network. Inappropriate wiring of these neuronal connections has serious consequences for the sensory, motor and cognitive functions of the nervous system.  During embryonic development, axons extend to their target via attractive and repulsive molecular guidance molecules. We have recently demonstrated that a molecule called Sonic Hedgehog (Shh) acts as a chemo-attractive molecule for the axons of certain neurons in the spinal cord.

One of Dr. Charron’s objectives is to identify and characterize the components of the Shh signalling pathway in axonal guidance. In addition to helping us understand the immense complexity underlying the wiring of the nervous system, this work will help to identify novel strategies to promote the proper guidance and rewiring of axons damaged by neurodegenerative diseases and brain or spinal cord injuries. 

 

Affiliations of the Laboratory:

McGill University
Department of Medicine, Division of Experimental Medicine
Department of Biology
Department of Anatomy and Cell Biology
Integrated Program in Neuroscience
Program in Neuroengineering

Université de Montréal
Department of Medicine
Program in Molecular Biology
Centre of Excellence in Neuromics of Université de Montréal (CENUM)

Find out more about us on the NeuroTree!

All rights reserved: IRCM 2011_110 avenue des Pins Ouest - Montréal (Québec) H2W 1R7 – Canada
.