Pour une liste complète et à jour des publications, cliquer ici.
Publications choisies
Yam PT*, Kent CB*, Morin S, Farmer WT, Alchini R, Lepelletier L, Colman DR, Tessier-Lavigne M, Fournier AE†, Charron F†. 14-3-3 Proteins Regulate a Cell-Intrinsic Switch from Sonic Hedgehog-Mediated Commissural Axon Attraction to Repulsion after Midline Crossing. Neuron 2012, 76(4):735-749. *Equal contribution †Co-corresponding authors
Peng J and Charron F. Lateralization of the human nervous system: genetics of mirror movements. Curr Opin Neurobiol 2012, [In press]
Fabre PJ and Charron F. VEGF guides commissural axons: a classic blood vessel trophic factor on the nerve's service. Med Sci (Paris) 2011, 27(12):1066-8
Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonnière L, Bernard M, van Horssen J, de Vries HE, Charron F, Prat A. The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science 2011, 334(6063):1727-31
Izzi L and Charron F. Midline Axon Guidance and Human Genetic Disorders. Clinical Genetics 2011, 80(3): 226-234
Izzi L*, Lévesque M*, Morin S, Laniel D, Wilkes BC, Mille F, Krauss RS, McMahon AP, Allen BL, and Charron F. Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Developmental Cell 2011, 20:788-801. *Equal contribution
Allen BL, Song JY, Izzi L, Althaus IW, Kang J-S, Charron F, Krauss RS, and McMahon AP. Overlapping roles and collective requirement for the co-receptors Gas1, Cdo and Boc in Shh pathway function. Developmental Cell 2011, 20:775-87.
Ruiz de Almodovar CE*, Fabre PJ*, Knevels E, Coulon C, Segura I, Haddick PCG, Aerts L, Delattin N, Strasser G, Oh W-J, Lange C, Vinckier S, Haigh J, Fouquet C, Henderson C, Gu C, Alitalo K, Castellani V, Tessier-Lavigne M, Chedotal A, Charron F†, and Carmeliet P†. VEGF mediates commissural axon chemoattraction through its receptor Flk1. Neuron 2011, 70:966-78. *Equal contribution †Co-corresponding authors
Camp D, Currie K, Labbé A, van Meyel DJ, and Charron F. IHog and Boi are essential for Hedgehog signaling in Drosophila. Neural Development 2010, 5:28.
Kent CB, Shimada T, Ferraro GB, Ritter B, Yam PT, McPherson PS, Charron F, Kennedy TE, and Fournier AE. 14-3-3 proteins regulate protein kinase activity to modulate growth cone turning responses. The Journal of Neuroscience. 2010, 30:14059-67.
Langlois SD, Morin S, Yam PT, and Charron F. Dissection and culture of commissural neurons from embryonic spinal cord. Journal of Visualized Experiments 2010, 25:(39). pii: 1773.
Srour M, Rivière JB, Pham JM, Dubé MP, Girard S, Morin S, Dion PA, Asselin G, Rochefort D, Hince P, Diab S, Sharafaddinzadeh N, Chouinard S, Théoret H, Charron F, Rouleau GA. Mutations in DCC cause congenital mirror movements. Science 2010, 328: 592.
Mastick GS, Farmer WT, Altick AL, Nural HF, Dugan JP, Kidd T, Charron F. Longitudinal axons are guided by slit/robo signals from the floor plate. Cell Adh Migr. 2010, Jul 18;4(3). [Epub ahead of print]
Fabre PJ, Shimogori T, Charron F. Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc. J Neurosci. 2010, 30: 266-75.
Yam PT, Langlois SD*, Morin S*, Charron F. Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway. Neuron 2009, 62: 349-62. *These authors contributed equally to this work.
Fabre P, Morin S, Charron F. Sonic hedgehog et Boc: une histoire de guidage axonal tres attirante. Sonic hedgehog and Boc: a very attractive story about axons. Med Sci 2008, 24: 129-31
Charron F and Tessier-Lavigne M. The Hedgehog, TGF-β/BMP and Wnt Families of Morphogens in Axon Guidance. Adv Exp Med Biol 2007, 621: 116-33
Okada A*, Charron F*, Morin S, Shin DS, Wong K, Fabre PJ, Tessier-Lavigne M, and McConnell SK. Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature 2006, 444: 369-73. *These authors contributed equally to this work.
Charron F and Tessier-Lavigne M. Novel Brain Wiring Functions for Classical Morphogens: A Role as Graded Positional Cues in Axon Guidance. Development 2005, 132: 2251-62
Charron F, Stein E, Jeong J, McMahon AP, and Tessier-Lavigne M. The Morphogen Sonic Hedgehog is an Axonal Chemoattractant that Collaborates with Netrin-1 in Midline Axon Guidance. Cell 2003, 113: 11-23
Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, and Crabtree GR. Neurotrophins and Netrins Require Calcineurin/NFAT Signaling to Stimulate Outgrowth of Embryonic Axons. Cell 2003, 113: 657-70
For a complete and updated list of publications, click here.Selected Publications
