The Clinic
Studying at IRCM
Core facilities
Molecular Genetics
Skip navigation links
Contact us

Home > Molecular Genetics > Publications
Home > Molecular Genetics > Publications
Research unit director

Complete list of publications (PDF)

Click here for a list of IRCM publications through PubMed.

Publications since 2005
Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L’Honoré A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J, The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes and Dev. 2012 (15 Oct), in press

Langlais D, Couture C, Balsalobre A, Drouin J. The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome. Mol Cell 2012, 47(1):38-49

Couture C, Saveanu A, Barlier A, Carel JC, Fassnacht M, Flück CE, Houang M, Maes M, Phan-Hug F, Enjalbert A, Drouin J, Brue T, Vallette S. Phenotypic Homogeneity and Genotypic Variability in a Large Series of Congenital Isolated ACTH-Deficiency Patients with TPIT Gene Mutations. J Clin Endocrinol Metab 2012, 97(3):E486-95

Budry L, Lafont C, El Yandouzi T, Chauvet N, Conéjero G, Drouin J, Mollard P. Related pituitary cell lineages develop into interdigitated 3D cell networks. Proc Nat Acad Sci 2011, 108, 30:12515-12520

Budry L, Couture C, Balsalobre A, Drouin J. The Ets factor Etv1 interacts with Tpit for pituitary POMC transcription. J Biol Chem 2011, 286(28):25387-25396

Langlais D, Couture C, Sylvain-Drolet G, Drouin J. A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells. Mol Endocrinol 2011, 25(2):348-359

Drouin J, Takayasu S. Autoimmunity: acquired versus inherited pituitary deficiency – same difference? Nat Rev Endocrinol, (commentary on Yamamoto M et al), 2011, 7(5):255-256

L’Honoré A, Ouimette JF, Lavertu-Jolin M, Drouin J. Pitx2 defines alternate pathways acting through MyoD during limb and somitic myogenesis. Development 2010, 137, 3847-3856; doi:10.1242/dev.053421

Jean-François Ouimette, Marisol Lavertu Jolin, Aurore L’honoré, Anthony Gifuni, Jacques Drouin. Divergent transcriptional activities determine limb identity. Nat. Commun. 1:35 doi: 10.1038 / ncomms1036 (2010).

Roussel-Gervais A, Bilodeau S, Vallette S, Berthelet F, Lacroix A, Figarella-Branger D, Brue T, Drouin J. Cooperation between Cyclin E and p27Kip1 in Pituitary Tumorigenesis. Mol Endocrinol. 2010 Jul 21 [Epub ahead of print]

Drouin J, Bilodeau S, Roussel-Gervais A. Stem cells, differentiation and cell cycle control in pituitary. Front Horm Res. 2010;38:15-24. Epub 2010 Jul 5.

Rambaud J, Desroches J, Balsalobre A, Drouin J. TIF1b/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77. J Biol Chem 2009, 284(21):14147-14156

Steve Bilodeau, Audrey Roussel-Gervais, Jacques Drouin. Distinct Developmental Roles of Cell Cycle Inhibitors p57Kip2 and p27Kip1 Distinguish Pituitary Progenitor Cell Cycle Exit from Cell Cycle Reentry of Differentiated Cells. Mol Cell Biol, 2009 7:1895–1908.

David Langlais, Catherine Couture, Aurélio Balsalobre*, Jacques Drouin*. Regulatory Network Analyses Reveal Genome-Wide Potentiation of LIF Signaling by Glucocorticoids and Define an Innate Cell Defense Response. PLoS Genet, 2008 4(10); e1000224.

Pierre-Luc Lavoie, Lionel Budry, Aurélio Balsalobre, Jacques Drouin. Developmental Dependence on NurRE and EboxNeuro for Expression of Pituitary Proopiomelanocortin. Molecular Endocrinology, 2008; 22(7):1647–1657.

Stijn P. De Langhe, Gianni Carraro, Denise Tefft, Changgong Li, Xin Xu, Yang Chai, Parviz Minoo, Mohammad K. Hajihosseini, Jacques Drouin, Vesa Kaartinen, Saverio Bellusci. Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by b-catenin Signaling. PLoS one, 2008; 1-12.

Thimios A. Mitsiadis, Jacques Drouin. Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes. Developmental Biology, 2008; 887–896.

Coulon V, L'Honoré A, Ouimette JF, Dumontier E, van den Munckhof P, Drouin J. A muscle-specific promoter directs Pitx3 gene expression in skeletal muscle cells. J Biol Chem. 2007; 282:33192-33200.

Drouin J, Bilodeau S, Vallette S. Of old and new diseases: genetics of pituitary ACTH excess (Cushing) and deficiency. Clin Genet 2007: 72: 175–182.

Sophie Vallette-Kasic, Catherine Couture, Aurelio Balsalobre, Yves Gauthier, Louise Metherell, Mehul Dattani, Jacques Drouin. The TPIT Gene Mutation M86R Associated with Isolated Adrenocorticotropin Deficiency Interferes with Protein: Protein Interactions. The Journal of Clinical Endocrinology & Metabolism 2007, 92(10):3991–3999.

Aurore L'Honoré, Vincent Coulon, Alexandre Marcil, Mélanie Lebel, Julien Lafrance-Vanasse, Philip Gage, Sally Camper, Jacques Drouin. Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development. Developmental Biology 307 (2007) 421–433.

Steve Bilodeau, Sophie Vallette-Kasic, Yves Gauthier, Dominique Figarella-Branger, Thierry Brue, France Berthelet, Andre Lacroix, Dalia Batista, Constantine Stratakis, Jeanette Hanson, Bjorn Meij, Jacques Drouin. Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease. Genes and Development, 2006; 20:2871-2886.

Naomi Weintrob, Jacques Drouin, Sophie Vallette-Kasic, Ellen Taub, Daphna Marom, Yael Lebenthal, Gil Klinger, Efrat Bron-Harlev, Mordechai Shohat. Low Estriol Levels in the Maternal Triple-Marker Screen as a Predictor of Isolated Adrenocorticotropic Hormone Deficiency Caused by a New Mutation in the TPIT Gene. Pediatrics, 2006;117;322-327.

Pepijn van den Munckhof, François Gilbert, Michel Chamberland, Daniel Lévesque, Jacques Drouin. Striatal neuroadaptation and rescue of locomotor deficit by L-dopa in aphakia mice, a model of Parkinson’s disease. Journal of Neurochemistry, 2006, 96, 160–170.

Charles MA, Suh H, Hjalt T, Drouin J, Camper SA, Gage PJ. PITX genes are required for cell survival and Lhx3 activation. Mol Endodrinol 2005, 19(7), 1893-1903.

Batsché E, Desroches J, Bilodeau S, Gauthier Y, Drouin J. Rb enhances p160/SRC coactivator-dependent activity of nuclear receptors and hormone responsiveness. J Biol Chem 2005, 280, 20:19746-19756.

Batsché E, Moschopoulos P, Drouin J. Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription. J Biol Chem 2005, 280, 16:16088-16095.

Sophie Vallette-Kasic, Thierry Brue, Anne-Marie Pulichino, Magali Gueydan, Anne Barlier, Michel David, Marc Nicolino, Georges Malpuech, Pierre Déchelotte, Cheri Deal, Guy Van Vliet, Monique De Vroede, Felix G. Riepe, Carl-Joachim Partsch, Wolfgang G. Sippell, Merih Berberoglu, Begüm Atasay, Francis de Zegher, Dominique Beckers, Jennifer Kyllo1, Patricia Donohoue, Martin Fassnacht, Stefanie Hahner, Bruno Allolio, C. Noordam, Leo Dunkel, Matti Hero, B. Pigeon, Jacques Weill, Sevket Yigit, Raja Brauner, Juan Jorge Heinrich, Elizabeth Cummings, Christie Riddell, Alain Enjalbert, Jacques Drouin (2004). Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death explained by TRIT gene mutations. JCEM 2005, 90: 1323-1331.

Maria Nudi, Jean-François Ouimette, Jacques Drouin (2004). Bone morphogenic protein (Smad)-mediated repression of proopiomelanocortin transcription by interference with Pitx/Tpit activity. Mol Endo 2005, 19: 1329-1342.

Christine Martens, Steve Bilodeau, Mario Maira, Yves Gauthier, Jacques Drouin (2004). Protein-protein interaction and transcriptional antagonism between the subfamily NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor. Mol Endo 2005, 19: 885-897.

All rights reserved: IRCM 2011_110 avenue des Pins Ouest - Montréal (Québec) H2W 1R7 – Canada