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Integrative molecular models of RNA polymerase IIA either (A) in solution or (B) in the pre-initiation complex. (C) A tentative model showing the close proximity of the CTD and the RNA exit channel. (D) The position of the CTD and the path of the promoter DNA are superimposed on a schematic representation of the structure of core RNA polymerase II bound to the SRB-mediator complex. (1999)

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Steps during transcriptional initiation (1999)

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Comparison of prokaryotic and eukaryotic transcriptional initiation (1999)

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Movement of TAFs from the core promoter region in order to bind PolII and the general transcription factors (1999)

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Isomerized PolII elongation complex in the absence (A) and presence (B) of TFIIF (1999)

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The molecular animation displayed is a low resolution version.
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