Post-doctoral position available immediately

The Biochemical Neuroendocrinology laboratory of Nabil G. Seidah at the Montreal Clinical Research Institute (IRCM) is searching for highly motivated and talented post-doc candidates to work on the biology and translational applications of the Proprotein Convertases PCSK9 and PCSK7 in cardiovascular diseases and cancer/metastasis. The position offers an extraordinary team-based science environment located in the heart of Montreal in the Canadian province of Quebec. The IRCM is world renown clinical research institute with multidisciplinary researchers from all over the world. The selected candidate(s) will enjoy opportunities for exciting biomedical research, technological innovations, education, and career development. Details about research in our lab can be found at: Nabil Seidah

Job duties
•    Develop protocols using antisense oligonucleotide (ASO) silencing and/or monoclonal antibodies in mouse models and human cells to treat the fatty liver disease (NASH) and cancer/metastasis including hepatocellular carcinoma.
•    Identify and characterize the molecular pathways that underly the functions of PCSK9 and PCSK7 in cells and in single or double knockout mice.
•    Dissect the functional consequences on LDL-cholesterol and triglycerides regulation of genetic variations in human PCSK7 or PCSK9 gene. 
•    Participate in lab meetings and national/international conferences.   

Minimum qualifications:
PhD in Biochemistry and/or Molecular and Cellular Biology obtained in the last 3 years.

Preferred qualifications :
•    Enthusiastic and technically competent
•    Critical thinking; excellent reading and writing skills
•    Able to work well in teams 
•    Fluent in English; some knowledge of French is an asset

How to apply:
Please send your CV, a cover letter and at least two letters of support from the PhD supervisor and senior colleagues to Dr. Nabil G. Seidah.

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