Sylvain Iceta

Is there a link between glycemic variability, cognition and disordered eating behaviors in type 1 diabetes?

Sylvain Iceta, MD, PhD
Associate Professor 
Department of Psychiatry and Neurosciences
Faculty of Medicine, Université Laval;
Clinician Investigator
Quebec Heart and Lung Institute Research Centre

This conference is hosted by Dr. Rémi Rabasa-Lhoret, MD, PhD. This conference is part of the 2022-2023 IRCM conference calendar.

In person: 
IRCM Auditorium
110, avenue des Pins O, H2W 1R7 Montreal
Wearing a mask is mandatory at all times

Online:
Zoom Link : https://zoom.us/j/95269762104
ID : 952 6976 2104
Code : 476372

IRCM conferences are set to occur under a hybrid format. However, please note that last-minute changes to online-only lectures may occur due to unforeseen circumstances. We invite you to visit this webpage again a few days before attending.

About this conference: 
As a long-term disease, type 1 diabetes (T1D) brings new challenges to patients and physicians including the handling of chronic complications; among which diabetes-related brain complications (e.g., cognitive function impairment). Cognitive function allows one to manipulate information and contribute to problem-solving skills. The underlying mechanisms responsible for cognitive impairment in patients with type 1 diabetes (PWT1D) are difficult to characterize. Chronic hyperglycemia, longer diabetes duration, severe and/or repeated hypoglycemic episodes have all been associated with a higher risk of cognitive impairment (e.g., dementia) in PWT1D. Few studies have assessed the role of glycemic variability, which might better reflect the broad spectrum of hyper/hypoglycemia frequency, magnitude and duration. Moreover, glycemic variability might also result in disturbed eating behavior (e.g., binge eating), as both hyperglycemia and hypoglycemia can modulate hunger and alter cognitive function. Such disordered eating behavior (DEB) can exacerbate glycemic fluctuations that may in turn worsen cognitive function. Impaired cognitive function can then lead to more difficulties to maintain adequate blood sugar levels and eating behavior, setting up a vicious circle. A better understanding of this phenomenon is essential.
During this conference we will describe disordered eating behaviors observed in patients living with T1DM; explore the potential mechanisms involved in both normal and disordered eating behaviors; and present our ongoing project exploring these relationships: The Sugar Swing Study.

About Sylvain Iceta: 
Sylvain Iceta is an Assistant Professor in the Department of Psychiatry and Neurosciences at Laval University. He is a psychiatrist specializing in consultation-liaison psychiatry, eating disorders, obesity and bariatric surgery. 
In 2019, he defended his doctoral thesis on impulsivity and food addiction and, the same year, he arrived in Quebec City to conduct postdoctoral research at the IUCPQ - Université Laval Research Center, where various studies on brain and behavioral changes following bariatric surgery are conducted. In 2022, Dr. Sylvain Iceta was one of the laureates of the Clinical Researcher - Junior 1 competition of the Fonds de recherche du Québec - Santé. His research program aims to better understand the mechanisms involved in a particularly common subtype of multimorbidity: the association between a mental health disorder and a physical health disorder. His work uses a dimensional approach to better characterize patients with physical-mental multimorbidity and to identify the biological factors involved in this association. 

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