The evolution of gut-derived metabolic medicines

Daniel J. Drucker, OC, MD, FRSC, FRS
Professor
Department of Medicine
Temerty Faculty of Medicine
University of Toronto
Lunenfeld-Tanenbaum Research Institute
Mount Sinai Hospital
Toronto, ON, Canad

This conference is hosted by:

• Clémence Schmitt: Vice-President of the ASSO & PhD candidate in the Molecular Mechanisms of Diabetes Research Unit.
• Gilberto Duran Bishop: President of the ASSO & PhD candidate in the Stem Cells and Cell Reprogramming Research Unit.

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This lecture will be held in person, in the IRCM Jacques-Genest Auditorium, but will also be broadcastl live on Zoom (Zoom Link)

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About this conference
This lecture will trace the mechanistic and therapeutic evolution of gut hormone-based therapies, starting with the incretin concept, later encompassing modern weight loss medicines, followed by demonstration of pleiotropic cardiorenal, hepatic and anti-inflammatory benefits in preclinical studies, subsequently validated in the clinic, across a wide range of cardiometabolic disorders. 

About Daniel J. Drucker
Dr. Daniel J. Drucker is a pioneering endocrinologist and Professor of Medicine at the University of Toronto, where he also serves as a Senior Scientist at the Lunenfeld-Tanenbaum Research Institute at Sinai Health. His groundbreaking research has fundamentally transformed the treatment of metabolic and intestinal disorders. Dr. Drucker is internationally recognized for his discovery and characterization of incretin hormones—specifically GLP-1 and GLP-2—and the enzyme DPP-4, which have led to life-changing therapies for type 2 diabetes, obesity, and short bowel syndrome.
 
His contributions have been recognized internationally through many of the highest honors in medicine and science. He is a Fellow of the Royal Society and has received numerous prestigious honors, including the 2025 Breakthrough Prize in Life Sciences, the Wolf Prize in Medicine, the Canada Gairdner International Award, the Banting Medal for Scientific Achievement, and the Endocrine Society's Fred Conrad Koch Lifetime Achievement Award.

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