Center for immunity, inflammation and infectious diseases
Co-leaders: Javier DiNoia and Wong-Kyung Suh
The 3i Centre brings together fundamental and clinician scientists with complementary expertise in immunity, inflammation, microbiology and infectious diseases. Its goals are to understand how the normal immune system works; to elucidate how diseases of the immune system develop; and to develop new means to modulate or harness the immune system to treat human diseases such as immunodeficiencies, autoimmune diseases, inflammatory bowel diseases, metabolic diseases, in-fections, and cancers. We use state-of-the-art technologies including genetics, genomics, prote-omics, cell biology and mouse models of human diseases, benefiting from the Primary Immunode-ficiencies Clinic at the IRCM. Our studies also include understanding cancers that develop from immune cells, like lymphoma and leukemia, determining how the microbiota and nutrition impact inflammation and immune responses, and uncovering the pathophysiology underlying viral infec-tions and post-viral conditions. While based at the IRCM, the 3i Centre collaborates with research-ers from other institutions in Montreal, Canada and across the world.
Discover our researchers