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Exploring new avenues to develop tomorrow’s medical knowledge through an approach that integrates basic and clinical research
Our research units are led by principal investigators who collaborate in a spirit of collegiality and with the vision of bridging the gap between research and patients. They train the next generation of scientists and are independent and creative minds who work tirelessly to improve health.
Martin Sauvageau, research director
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We perform functional assays to determine the role of lncRNAs in human and animal cells using genome editing, CRISPR systems and antisense oligos technologies.
We dissect the composition of RNA-based machines and characterize their molecular activities using state-of-the-art biochemical, molecular as well as short- and long-read sequencing-based approaches. We also work to develop novel RNA-based tools for targeted genome regulation.
We characterize the in vivo roles of lncRNAs using animal models and xenografts combined with a suite of CRISPR-based genome engineering approaches. We also actively develop novel mRNA-based and RNA-targeting therapeutics.
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514 987-5599
martin.sauvageau@ircm.qc.ca
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